CONFORMATIONAL MASKING AND RECEPTOR-DEPENDENT UNMASKING OF HIGHLY CONSERVED ENV EPITOPES RECOGNIZED BY NON-NEUTRALIZING ANTIBODIES THAT MEDIATE POTENT ADCC AGAINST HIV-1

Conformational Masking and Receptor-Dependent Unmasking of Highly Conserved Env Epitopes Recognized by Non-Neutralizing Antibodies That Mediate Potent ADCC against HIV-1

The mechanism of antibody-mediated protection is a major focus of HIV-1 vaccine development and a significant issue in the control of viremia.Virus neutralization, Fc-mediated effector function, or both, are major mechanisms of antibody-mediated protection against HIV-1, although other mechanisms, such as virus aggregation, are known.The interplay

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Inihibition of Glycolysis by Using a Micro/Nano-Lipid Bromopyruvic Chitosan copyright as a Promising Tool to Improve Treatment of Hepatocellular Carcinoma

Glucose consumption in many types of cancer cells, in particular hepatocellular carcinoma (HCC), was followed completely by over-expression of type II hexokinase (HKII).This evidence has been used in modern pharmacotherapy to discover therapeutic target against glycolysis in cancer cells.Bromopyruvate (BrPA) exhibits antagonist property against HKI

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